女人张开腿让男人添,在线?亚洲?国产 欧美,嫩草乱码一区三区四区,特级做A爰片毛片免费69

Expert forum

首頁(yè) 專家論壇 標(biāo)本專家Circulating Tumor Cells: A Review of Non-EpCAM-Based Approaches for Cell Enrichment and Isolation.
注冊(cè)

Circulating Tumor Cells: A Review of Non-EpCAM-Based Approaches for Cell Enrichment and Isolation.

2017-12-08 07:14來(lái)源:原版作者:Gabriel MT

BACKGROUND:

Circulating tumor cells (CTCs) are biomarkers for noninvasively measuring the evolution of tumor genotypes during treatment and disease progression. Recent technical progress has made it possible to detect and characterize CTCs at the single-cell level in blood.

CONTENT:

Most current methods are based on epithelial cell adhesion molecule (EpCAM) detection, but numerous studies have demonstrated that EpCAM is not a universal marker for CTC detection because it fails to detect both carcinoma cells that undergo epithelial-mesenchymal transition (EMT) and CTCs of mesenchymal origin. Moreover, EpCAM expression has been found in patients with benign diseases. A large proportion of the current studies and reviews about CTCs describe EpCAM-based methods, but there is evidence that not all tumor cells can be detected using this marker. Here we describe the most recent EpCAM-independent methods for enriching, isolating, and characterizing CTCs on the basis of physical and biological characteristics and point out the main advantages and disadvantages of these methods.

SUMMARY:

CTCs offer an opportunity to obtain key biological information required for the development of personalized medicine. However, there is no universal marker of these cells. To strengthen the clinical utility of CTCs, it is important to improve existing technologies and develop new, non-EpCAM-based systems to enrich and isolate CTCs.

版權(quán)聲明:

本網(wǎng)站所有注明“來(lái)源:“陽(yáng)普醫(yī)療”的文字、圖片和音視頻資料,版權(quán)均屬于陽(yáng)普醫(yī)療所有,非經(jīng)授權(quán),任何媒體、網(wǎng)站或個(gè)人不得轉(zhuǎn)載,授權(quán)轉(zhuǎn)載時(shí)須注明

“來(lái)源:陽(yáng)普醫(yī)療”。本網(wǎng)所有轉(zhuǎn)載文章系出于傳遞更多信息之目的,且明確注明來(lái)源和作者,不希望被轉(zhuǎn)載的媒體或個(gè)人可與我們聯(lián)系,我們將立即進(jìn)行刪除處理。

網(wǎng)友評(píng)論:

  • <center id="wvtgz"><tr id="wvtgz"><track id="wvtgz"></track></tr></center>
  • <ul id="wvtgz"></ul>

      
      
        1. 主站蜘蛛池模板: 古浪县| 平原县| 十堰市| 龙州县| 孝感市| 新乐市| 巴楚县| 宣武区| 武乡县| 池州市| 来凤县| 汝州市| 三江| 金寨县| 道孚县| 隆回县| 宜州市| 神池县| 广宁县| 白银市| 新平| 襄汾县| 邢台市| 海晏县| 波密县| 盐亭县| 大洼县| 新竹县| 临潭县| 河南省| 三明市| 蓝田县| 南皮县| 驻马店市| 无棣县| 延吉市| 卫辉市| 馆陶县| 南部县| 襄樊市| 三原县|