女人张开腿让男人添,在线?亚洲?国产 欧美,嫩草乱码一区三区四区,特级做A爰片毛片免费69

Expert forum

首頁 專家論壇 標本專家Functional Studies on Viable Circulating Tumor Cells.
注冊

Functional Studies on Viable Circulating Tumor Cells.

2017-12-08 08:01來源:原版作者:Pantel K

BACKGROUND:

Research on circulating tumor cells (CTCs) as new biomarkers has received great attention over the past decade. In particular, the capture and analysis of CTCs as "liquid biopsies" provides the possibility to avoid invasive tissue biopsies, with obvious implications in cancer diagnostics.

CONTENT:

The focus of this review is to describe and discuss how functional studies on viable CTCs can enlarge the spectrum of applications of liquid biopsies, with emphasis on breast, prostate, colon, and lung cancer as the major tumor entities in industrialized countries. The low number of CTCs in the peripheral blood of most cancer patients makes challenging the in vitro culture of CTCs. Epithelial tumor cells are difficult to culture, even when starting with millions of tumor cells. Recently, several groups have achieved important advances in the in vitro and in vivo expansion of CTCs from cancer patients at very advanced stages with higher amounts of CTCs. Here, we present current technologies to enrich and detect viable human CTCs, including positive and negative enrichment strategies that are based on antigen expression and physical properties of CTCs. We also discuss published data about functional studies on CTCs that use in vitro and in vivo models.

SUMMARY:

Functional analyses on CTCs offer the possibility to identify the biological properties of metastatic cells, including the identification of metastasis-initiating cells. Moreover, CTC-derived cell lines and xenografts might reveal new therapeutic targets and can be used for drug screening.

(Clin Chem. 2016 Feb;62(2):328-34. )

版權聲明:

本網站所有注明“來源:“陽普醫療”的文字、圖片和音視頻資料,版權均屬于陽普醫療所有,非經授權,任何媒體、網站或個人不得轉載,授權轉載時須注明

“來源:陽普醫療”。本網所有轉載文章系出于傳遞更多信息之目的,且明確注明來源和作者,不希望被轉載的媒體或個人可與我們聯系,我們將立即進行刪除處理。

網友評論:

  • <center id="wvtgz"><tr id="wvtgz"><track id="wvtgz"></track></tr></center>
  • <ul id="wvtgz"></ul>

      
      
        1. 主站蜘蛛池模板: 绥宁县| 庆城县| 浙江省| 南投县| 嫩江县| 柳林县| 石家庄市| 望城县| 九龙县| 衡阳县| 商南县| 莱西市| 博兴县| 广元市| 白玉县| 靖边县| 大关县| 平武县| 吴川市| 德庆县| 响水县| 霸州市| 铜川市| 尉氏县| 库车县| 万年县| 新疆| 西和县| 鹿泉市| 兴仁县| 黎城县| 沙洋县| 志丹县| 泾川县| 胶州市| 横峰县| 体育| 维西| 兴业县| 浑源县| 来凤县|